Hi
@Hope_eternal -- I haven't been keeping up with this thread, but your son's situation keeps coming up in my mind a lot. The reason being is I can't help but think it's "possible" most of your son's ME/CFS symptoms are a result of his IBS. Which makes me think that the following 20-minute video might be helpful.
How I Reversed Chronic Constipation Using Coffee Enemas! | SIBO IBS-C Gallstones
I watch YouTube videos all the time, and have watched innumerable ones on health of the years. This video is one of my all time favorites, because it mirrors so much of my own philosophy about GI health and overall health. Since your son has an interest in science, I think he might appreciate some of the physiology descriptions by this college age student.
He mentions constipation in his title, but I think that word could easily be replaced by SIBO, or IBS, or just about any other major or minor GI issue. One thing I really like about this video is the young man's perspective and approach. He is relentless! It seems clear to me that no matter what health problem he had encountered, he would have used this same approach to solving it. My own philosophy over the years is to be as relentless, resourceful and resilient as I could be. The young man in this video seems to fit all those criteria.
I also seem to recall your son is taking Prozac. And also that he had a good mood reaction from taking some kind of herb or supplement (curcumin?). A couple of things: My understanding is Prozac can be very hard on the GI tract, something to consider given your son's IBS. Also, if your son can get an upliftment from some kind of herb or supplement, might it suggest he may not need a drug, but something to support his system. Just FWIW.
All the Best to you and your son...