Welcome to Phoenix Rising!
Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
To become a member, simply click the Register button at the top right.
Hi
I am taking SAMe and TMG as co factors.
Are there any other methyl donors that we should be including as I have read in several places that DMG is a methyl donor too. Should we consider taking this?
I am not taking glutathione or NAC, per instructions.
Thanks
Thanks Freddd
All supplements have been listed at post #23 at http://forums.phoenixrising.me/showthread.php?16127-Why-arenDeplin/page3.
I am not taking choline. Should I be?
Hi Topaz,
THAT IS NOT MY LIST. Part of it swas copied. The rest of it came from presumably thge person posting it and hasd things I would never suggest, brands I 'm not suggesting are better, all sorts of stuff. Go to the BASICS thead and find it there.
Hi Topaz,
THAT IS NOT MY LIST. Part of it swas copied. The rest of it came from presumably thge person posting it and hasd things I would never suggest, brands I 'm not suggesting are better, all sorts of stuff. Go to the BASICS thead and find it there.
Freddd
I think we have crossed wires. You asked me in two posts in response to my questions and problems to list what I am taking and the link referred to above above (post #23 http://forums.phoenixrising.me/showthread.php?16127-Why-arenDeplin/page3) is what I am currently taking.
It is all the supplements comprising your Active protocol. I only use your brands where specified and made my own choice when brand is not specified.
The "other " supplements are those prescribed by my practitioner and I listed them n response to your query for a list of my supplements so you could help me. I separated them from the list of your protocol basics.
Thanks
Your list says - P5P, how much? I take 50mg P5P. Many people find the amount in their B complex is enough, but I seem to need more. 50mg gives me a perfect homocysteine reading. 200mg does not change my homocysteine reading beyond that. So as far as methylation is concerned I think 50mg will do it, unless you have high blood pressure (which can be caused by high homocysteine, in which case you might consider more until you can get your bp down). Other reasonz you might take more is to protect the kidneys from glycation due to blood sugar or to help turn 5-HTP into serotonin.
choline is needed to prevent fatty liver. I get it from eggs which I eat every day. I dont know if the amount in your B complex is enough. According to this patent, choline requirements are 550mg/day for men and 425 for women: http://www.freshpatents.com/-dt20101118ptan20100292339.php. I dont know how hard that is to get. It seems like I get it by diet and B complex. No fatty liver! However, I have noticed in the past that my brain feels like it's been rubbed with Vick Vaporub if I take a higher amount of choline (I forget how high). It feel sjust the way it feels if I take that high dose mfolate (the 15 pill dose or whatever) but w/o the instability feeling of needing more mB12, more this - more that - to balance it. I have 3 BHMT mutations (TMG path) so theoretically I can use more choline/bdetaine than the average person. I do not know if TMG can also prevent fatty liver - I never heard any such thing.
Anyway choline is probably in your B complex so may be enough for now. TMG is enough for methylation.
Rydra
Freddd...OMG take a look at that patent above! I cannot BELIEVE they let them patent that! All someone did is read the studies which clearly show a higher need for choline based on certain genes and THEY PATENTED THAT! Like - what? We aren't allowed to have a brain cell and READ the studies?!!! It's like someone patenting that f you have the gene that cant break down folic acid then you need methylfolate. How can anyone patent such a thing? These are natural substances and the genetic tests are done by somebody else and on the internet fr all to read! I mean it's like patenting that when you feel thirsty you need to drink!
I wonder if we wont be allowed to buy supplements because someone has a patent?! I
I sorry. Somebody else was asking what I suggested and questioned me about why certains things were on there. That was all I meant. I had no idea why some of the items are there and the ones that were lacked my included explanations. You were posting it of course in answer to my question, thaankyou. Again, sorry I didn't explain it better.
Your list says - P5P, how much? I take 50mg P5P. Many people find the amount in their B complex is enough, but I seem to need more. 50mg gives me a perfect homocysteine reading. 200mg does not change my homocysteine reading beyond that. So as far as methylation is concerned I think 50mg will do it, unless you have high blood pressure (which can be caused by high homocysteine, in which case you might consider more until you can get your bp down). Other reasonz you might take more is to protect the kidneys from glycation due to blood sugar or to help turn 5-HTP into serotonin.
choline is needed to prevent fatty liver. I get it from eggs which I eat every day. I dont know if the amount in your B complex is enough. According to this patent, choline requirements are 550mg/day for men and 425 for women: http://www.freshpatents.com/-dt20101118ptan20100292339.php. I dont know how hard that is to get. It seems like I get it by diet and B complex. No fatty liver! However, I have noticed in the past that my brain feels like it's been rubbed with Vick Vaporub if I take a higher amount of choline (I forget how high). It feel sjust the way it feels if I take that high dose mfolate (the 15 pill dose or whatever) but w/o the instability feeling of needing more mB12, more this - more that - to balance it. I have 3 BHMT mutations (TMG path) so theoretically I can use more choline/bdetaine than the average person. I do not know if TMG can also prevent fatty liver - I never heard any such thing.
Anyway choline is probably in your B complex so may be enough for now. TMG is enough for methylation.
Rydra
Freddd...OMG take a look at that patent above! I cannot BELIEVE they let them patent that! All someone did is read the studies which clearly show a higher need for choline based on certain genes and THEY PATENTED THAT! Like - what? We aren't allowed to have a brain cell and READ the studies?!!! It's like someone patenting that f you have the gene that cant break down folic acid then you need methylfolate. How can anyone patent such a thing? These are natural substances and the genetic tests are done by somebody else and on the internet fr all to read! I mean it's like patenting that when you feel thirsty you need to drink!
I wonder if we wont be allowed to buy supplements because someone has a patent?! I
Hi Topaz,
Would you describe what kinds of effects you had from starting Mb12, Metafloin, adb12, SAM-e and TMG. DMG is a very weak methyl donor compared to TMG or Choline (TMG with another methyl group, 4 in all).
Freddd
You say that DMG is a very weak methyl donor compared to TMG or Choline. Do you suggest supplementing with choline as it is not listed in your protocol?
You also say "TMG with another methyl group, 4 in all". What do you mean by "4 in all"?
Thank you
[...]DMG is a methyl donor too. Should we consider taking this?
hi Topaz
I don't know if you have any depressive type symptoms, but if so, I'd be very careful in adding any Choline because it can make symptoms worse for many.
Freddd
Would you be able to look at the list of what Im taking per the link above (you asked me to post what I was taking in 2 places and I posted the full list in the post above)
For 2 days now in an attempt to get rid of the extreme brain fog (and newly onset depression - easy to tears adn very very emotional) I have not taken anything other than 1 methyl b daily, 1/4 adb12 and 2 folates - even vitamins that I was taking long before commencing methylation have been dropped.
Maybe Im chopping and changing too much but I figure a few days or aweek without in an attempt to shift this brain fog.
Thanks
Hi
I am taking SAMe and TMG as co factors.
Are there any other methyl donors that we should be including as I have read in several places that DMG is a methyl donor too. Should we consider taking this?
I am not taking glutathione or NAC, per instructions.
Thanks