I'm following Dr Sarah Myhill's methylation protocol, starting low and slow
I meant to answer your question about glutathione. You can read the first maybe 10-15 pages of this post and I'm pretty sure that's where Fred explains a glutathione experiment that they did, which he believed drastically reduced B12 in the body and was dangerous. Partly this was based on what was visible in the urine(I assume pink color?) And partly based on how people were feeling and going backward in months or progress. I think he said (or I read somewhere) that there are other authorities that have concerns about glutathione.
This was a tough one for me bc NAC (which he also discourages) is believed in the tinnitus communities to either improve or at least prevent worsening of that condition.
Still, I stopped NAC supps bc it didn't sound like it would be worth taking a chance.
On a side note, I just started taking Lugol's Iodine bc of a vaginal infection / trying to avoid antibiotics that really harmed my gut 1.5 years ago. I have learned that iodine helps increase acid in the stomach. And I decided to read a book about iodine bc I was a little scared to take it. This book, written by a doctor and with a bunch of case studies and cites to medical studies, claim that high dose iodine cures a bunch of stuff including sometimes (not sure how often) chronic fatigue. I'm only planning to take this short-term for now. But I'm still reading the book and might change my mind as far as continuing.
I've also been watching videos about benfothiamine. That is supposed to help digestion in higher doses, too. I added benfomax from Pure a few weeks ago, and have decided to increase my dose (still no where near the highest doses recommended by some nutritionist on YouTube). He interviewed a man who had taken high doses for gastroparesis with very good results. That's something I'm testing.
I also took more iron yesterday. Still not recommended doses based on my level of deficiency. But like 57 mg from two different brands. I took 20 mg heme at night. My BP was still low but it was better. I still needed potassium overnight to correct low BP -- and that was disappointing bc I had skipped my B12 injection that day (planning only to inject every other day bc of this BP issue). I was hoping those two things would help more.
I'm still convinced the iron is playing a big role. My iron is just ready too low.
Last thing is that my reflux and tinnitus, my two worst symptoms prior to starting B12, have drastically improved! I'm eating many more foods that I couldn't tolerate before. And quite a few other symptoms have disappeared.
Unfortunately, I still have stomach distension. And this low iron / BP is concerning. Plus -- the reflux is not gone, which is the only acceptable end point for me without continuing to try everything.
But it's a lot better. I even managed to eat a small portion of red meat with tomato sauce yesterday with only the most minimal reaction. That would have caused a severe reaction weeks ago. And I've returned to eating my one cup of blueberries on mueseli every morning. That also would have burned my throat before.
I guess I should be happy but the distension is still really upsetting. And this new low BP is still the worst medical problem I've ever experienced -- and that comes with new really bad fatigue when it is happening.
I've also been exercising daily -- ran 6 miles yesterday. During my runs, I drink coconut water with added Utah sea salt from Trace Minerals.
Fatigue hits in the evening whenever my BP starts getting low, and usually gets better when I drink potassium. (Occasionally it seems like I need methylfolate for this new fatigue, too. Like sometimes it's potassium, sometimes methylfolate.)
This is all a lot, and I never was the type to want to take supplements. Generally, I don't believe in them. But my symptoms aren't acceptable without trying everything -- and regular docs at this point have nothing to offer for what have been debilitating symptoms.
I'm seeing a new naturopath highly recommended by a good friend next week. His undergrad was biochemistry at Stanford. So I'm very hopeful that he can help me figure out how to prevent the low BP and still continue the injections!