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immunotherapy technique for autoimmune diseases April 1, 2024 Mayo Clinic

K

keepontruckin

Senior Member
Messages
214
https://www.sciencedaily.com/releases/2024/04/240401190419.htm

Scientists have developed an immunotherapy strategy that potentially lays the groundwork for treating a spectrum of autoimmune diseases.
The new technique, detailed in a preclinical study published in Nature Biomedical Engineering, involves combining chimeric antigen receptors (CAR) with mesenchymal stromal cells (MSC), resulting in engineered stem cells known as CAR-MSCs.

"The pioneering approach shows potential in targeting inflammatory disease sites more precisely and improving immunosuppression and healing outcomes," says Saad Kenderian, M.B., Ch.B., a principal investigator and hematologist at Mayo Clinic. "We're planning to study interventions that minimize the need for long-term medications for autoimmune diseases."
 
Faith2007

Faith2007

Senior Member
Messages
108
Location
Montana, USA
So my question is, how would this differ from current stem cell therapy? Will this be a less expensive option?

Stem cell therapy is completely cost prohibitive in the USA, where I've been quoted treatments cost around $5000 dollars each from two different sources. I've been told by my CFIDS specialist that the treatment should be done every 3 months.

So I have a Christian holistic doctor that amazingly offered me Chinese stem cell therapy at her cost, which was dirt cheap. I started it just over 2 months ago. I have autoimmune thyroiditis and immune deficiency. What I can tell you is that I felt a decrease in pain in my neck, where I have the most pain, but the effect was strongest closest to the shot, and it doesn't completely remove the pain. I still have to do my neck exercises and stretches and get adjusted by a chiropractor every three weeks so it doesn't become too painful for me. I didn't notice an effect on my energy levels, but I got COVID-19 four or five weeks after the treatment, which hasn't helped me determine the results very well.

My doctor also has access to placenta stem cell therapy, which I would have preferred, but she wanted to try Chinese stem cell therapy on me first.

Here is an article entitled "Development and regulation of stem cell‐based therapies in China":
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357352/

Here is an article entitled "Placental-derived stem cells: Culture, differentiation and challenges":
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444616/


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