I wanted to get an idea about people’s experience with BPC-157.
So I have long covid (vax) induced CFS/ME complicated by SFN (biopsy proven), dysautonomia (hyperPOTS) and mitochondrial myopathy (biopsy proven). Also diagnosed with MS during this although neurologist is unsure of the diagnosis but continues to keep me on B cell depleting therapy. This is my third year with all of these issues and I am on propranolol, guanfacine, tadalafil and B cell depleting therapy. I also take ARA 290 and mitochondrial supplements and some other vitamins.
Well I started BPC 157 250mcg BID around three weeks ago and everything has been going really well. Almost immediately I noticed a change in my resting heart rate (60s -> 50s) and my orthostatic heart rate (100s -> 70/80s). Overall I felt better with more energy. I noticed in the afternoon before my second dose I would start getting agitated and almost panic feeling. This would go away after dosing my evening dose. I also noticed in the evening I would have bright red ears that burned. I didn’t think to much of this because I have raynauds and erythromelalgia from my dysautonomia. Last night I took my second dose around 10 and then around 1AM I had the onset of a cluster headache (unilateral orbital pain that was worst pain I’ve experienced with same side nasal discharge and Horners syndrome). It was so bad I drove to the ER but didn’t go in because it subsided around 30 minutes after it started. I had cluster headaches around 7 or 8 years ago when I was on an SSRI at the time but none have happened since.
I tried looking up side effects of BPC but there are limited human studies. Could this be serotonin or histamine related? I wonder why I feel so good on it and don’t want to stop if I don’t have to. Most people with side effects report anxiety while taking or a high heart rate while taking it - the opposite of me. I took today off and of course my resting heart rate and orthostatic heart rate jumped back up. I had been feeling so good on it for the last few weeks that I bought a three month supply so don’t want it to go to waste. I thought about TB500 but read it may not be great with autoimmune conditions or current immunosuppressant medications.
Any insight is appreciated!
So I have long covid (vax) induced CFS/ME complicated by SFN (biopsy proven), dysautonomia (hyperPOTS) and mitochondrial myopathy (biopsy proven). Also diagnosed with MS during this although neurologist is unsure of the diagnosis but continues to keep me on B cell depleting therapy. This is my third year with all of these issues and I am on propranolol, guanfacine, tadalafil and B cell depleting therapy. I also take ARA 290 and mitochondrial supplements and some other vitamins.
Well I started BPC 157 250mcg BID around three weeks ago and everything has been going really well. Almost immediately I noticed a change in my resting heart rate (60s -> 50s) and my orthostatic heart rate (100s -> 70/80s). Overall I felt better with more energy. I noticed in the afternoon before my second dose I would start getting agitated and almost panic feeling. This would go away after dosing my evening dose. I also noticed in the evening I would have bright red ears that burned. I didn’t think to much of this because I have raynauds and erythromelalgia from my dysautonomia. Last night I took my second dose around 10 and then around 1AM I had the onset of a cluster headache (unilateral orbital pain that was worst pain I’ve experienced with same side nasal discharge and Horners syndrome). It was so bad I drove to the ER but didn’t go in because it subsided around 30 minutes after it started. I had cluster headaches around 7 or 8 years ago when I was on an SSRI at the time but none have happened since.
I tried looking up side effects of BPC but there are limited human studies. Could this be serotonin or histamine related? I wonder why I feel so good on it and don’t want to stop if I don’t have to. Most people with side effects report anxiety while taking or a high heart rate while taking it - the opposite of me. I took today off and of course my resting heart rate and orthostatic heart rate jumped back up. I had been feeling so good on it for the last few weeks that I bought a three month supply so don’t want it to go to waste. I thought about TB500 but read it may not be great with autoimmune conditions or current immunosuppressant medications.
Any insight is appreciated!
