https://www.sciencedaily.com/releases/2024/02/240228114328.htm
I thought this was interesting. I don't know whether it would have real use as a treatment, but if you believe that glymphatic dysfunction plays a role in ME (@Rufous McKinney), it seems easy enough to experiment with. A 40 Hz flashing light and/or sound pulse is easy to generate with a simple electronic circuit, a simple computer program, or even an electric motor spinning a disk (with light hole and clicker) at 2400 rpm (not that building anything is really simple when you have ME).
I think it's interesting that the brain has specialized neurons that react to such a frequency, and that exposure to this input can affect capillary pulsation and fluid flow through astrocytes. The brain is not a simple network of electrical circuits; it's really complex with all these hard-to-notice interactions. ME could involve one or more of these subtle interactions, possibly one not discovered yet.
I thought this was interesting. I don't know whether it would have real use as a treatment, but if you believe that glymphatic dysfunction plays a role in ME (@Rufous McKinney), it seems easy enough to experiment with. A 40 Hz flashing light and/or sound pulse is easy to generate with a simple electronic circuit, a simple computer program, or even an electric motor spinning a disk (with light hole and clicker) at 2400 rpm (not that building anything is really simple when you have ME).
I think it's interesting that the brain has specialized neurons that react to such a frequency, and that exposure to this input can affect capillary pulsation and fluid flow through astrocytes. The brain is not a simple network of electrical circuits; it's really complex with all these hard-to-notice interactions. ME could involve one or more of these subtle interactions, possibly one not discovered yet.